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Model Checking of Software Systems under Weak Memory Models
When a program is compiled and run on a modern architecture, different optimizations may be applied to gain in efficiency. In particular, the access operations (e.g., read and write) to the shared memory may be performed in an out-of-order manner, i.e., in a different order than the order in which the operations have been issued by the program.
Understanding Heparan Sulfate Biosynthesis and Functional Implications of Heparanase
Heparan sulfate (HS) proteoglycans are present on the plasma membrane of all animal cells studied so far and are a major component of extracellular matrices. Heparanase is an endo-ß-glucuronidase that cleaves HS chains at internally located ß-glucuronidic linkages1. Except its conventional enzymatic function, non-enzyme function and its function in the nucleus have been demonstrated recently.
Adhesion-dependent mechanisms regulating mitosis
The current thesis describes new data on the adhesion-linked molecular mechanisms regulating cytokinesis and centrosomes.
Drug discovery against leishmaniasis: Bio- and chemoinformatic guided strategies for target evaluation and hit identification
The overall aim of this thesis is to aid in drug discovery against leishmaniasis – primarily using bio- and chemoinformtic approaches.
Biological Aspects of Peripartum Depression
Peripartum depression affects around 12% of women in pregnancy and postpartum, and about 2–3% of European pregnant women use antidepressants, mostly selective serotonin reuptake inhibitors (SSRIs).
Disputation: Dynamics of Magnetic Molecules under Electrical Control
This thesis theoretically studies the dynamics of molecular magnets under electrical control.
Disputation: Ion dynamics and structure of collisionless shocks in space
This thesis addresses the physics of collisionless shocks using spacecraft observations of the Earth's bow shock, particularly understanding the ion dynamics and shock structure for different shock conditions.
Adapting sonar systems for monitoring ocean energy technologies
This thesis focus on a sustainable implementation of wave, tidal and offshore wind power, wherefore there is a need to investigate more about the prerequisites and consequences ocean energy can have on the marine environment. For that, reliable, cost effective and continuous environmental monitoring framework is necessary in order to support and safeguard ocean energy operations.
“This is the Face of an Atheist”: Performing Private Truths in Precarious Publics
The primary aim of this dissertation is to gain a greater understanding of the particular vulnerabilities attached to wo/men publicly performing atheist selves on YouTube.
Treatment of Acute Uncomplicated Colonic Diverticulitis
The overall aim of this thesis was to evaluate the clinical management of AUD with regard to the no-antibiotic policy and its long-term effect, treatment on an outpatient basis and the potential health-care cost savings.
Cladophora Cellulose-based Separators for Lithium Batteries
In this thesis, a new type of material, i.e. Cladophora cellulose, is used to manufacture separators for LIBs and lithium-metal batteries (LMBs). The separators, made with Cladophora cellulose fibers via a straightforward paper making method, possess several advantages compared to conventional polyolefin separators.
Antibacterial Effect and Inflammatory Response in Relation to Antibiotic Treatment of Sepsis
This thesis aimed to investigate the anti-bacterial properties and antibiotic-induced inflammatory responses of ß-lactam antibiotic compared with effects of the addition of an aminoglycoside in clinically relevant E. coli porcine intensive care sepsis/septic shock models. We also studied the host's antibacterial capacities in primary and secondary sepsis.
Deliberation, against all odds?: The critical prospects of mini-publics
In recent decades, the theory of deliberative democracy has encountered multiple challenges. In this thesis, I explore the prospects of a particular type of deliberative democratic institution – deliberative mini-publics – in three essays.
Studies of cAMP and Ca2+ signaling in pancreatic islet cells
The blood glucose-lowering and -elevating hormones insulin and glucagon are released from the pancreatic islet β- and α-cells, respectively. The intracellular messengers Ca2+ and cAMP have central roles in controlling the secretion of both hormones, but the underlying mechanisms are incompletely understood.